000			02904cam a22003854a 4500
003			OCoLC
005			20251028092235.0
008			051102s2002 maua b 001 0 eng
001			ocm48100379
010			_a 2001051559
015			_aGBA2-Y0662
019			_a50214449 _a51622921
020			_a0674007468 (alk. paper)
029	1		_aUKM _bbA2Y0662
029	1		_aUKM _bbA248852
035			_a(Sirsi) i9780674007468
035			_a(Sirsi) i9780674007468
035			_a(Sirsi) i9780674007468
035			_a(Sirsi) i9780674007468
035			_z(Sirsi) 156617
040			_aDLC _cDLC _dYDX _dUKM _dWSL _dAGL _dBAKER _dVF$
042			_apcc
050	0	0	_aQH491 _b.K387 2002
090			_aQH 491 .K387 2002
100	1		_aKeller, Evelyn Fox, _d1936-2023.
245	1	0	_aMaking sense of life : _bexplaining biological development with models, metaphors, and machines / _cEvelyn Fox Keller.
260			_aCambridge, Mass. : _bHarvard University Press, _c2002.
300			_axii, 388 p. : _bill. ; _c22 cm.
504			_aIncludes bibliographical references (p. [351]-381) and index.
505	0		_aSynthetic biology and the origin of living form -- Morphology as a science of mechanical forces -- Untimely births of a mathematical biology -- Genes, gene action, and genetic programs -- Taming the cybernetic metaphor -- Positioning positional information -- The visual culture of molecular embryology -- New roles for mathematical and computational modeling -- Synthetic biology redux--computer simulation and artificial life.
520			_aPublisher's description: What do biologists want? If, unlike their counterparts in physics, biologists are generally wary of a grand, overarching theory, at what kinds of explanation do biologists aim? How will we know when we have "made sense" of life? Such questions, Evelyn Fox Keller suggests, offer no simple answers. Explanations in the biological sciences are typically provisional and partial, judged by criteria as heterogeneous as their subject matter. It is Keller's aim in this bold and challenging book to account for this epistemological diversity--particularly in the discipline of developmental biology. In particular, Keller asks, what counts as an "explanation" of biological development in individual organisms? Her inquiry ranges from physical and mathematical models to more familiar explanatory metaphors to the dramatic contributions of recent technological developments, especially in imaging, recombinant DNA, and computer modeling and simulations. A history of the diverse and changing nature of biological explanation in a particularly charged field, Making Sense of Life draws our attention to the temporal, disciplinary, and cultural components of what biologists mean, and what they understand, when they propose to explain life.
650		0	_aDevelopmental biology.
999			_c98664 _d98664