Includes bibliographical references.

Defining and addressing the problem / Kathleen M. Carroll and William R. Miller -- The forest and the trees : addiction as a complex self-organizing system / Warren K. Bickel and Marc N. Potenza -- The neurobiology of addiction : a hedonic Calvinist view / George F. Koob -- What can human brain imaging tell us about vulnerability to addiction and to relapse? / Anna Rose Childress -- Genetics of substance use disorders / Deborah Hasin, Mark Hatzenbuehler, and Rachel Waxman -- Natural change and the troublesome use of substances : a life-course perspective / Carlo C. Diclemente -- Developmental perspectives on the risk for developing substance abuse problems / Victor M. Hesselbrock and Michie N. Hesselbrock -- Comorbid substance use disorders and psychiatric disorders / Kim T. Mueser ... [et al.] -- Motivational factors in addictive behaviors / William R. Miller -- Racial and gender differences in substance abuse : what should communities do about them? / Harold D. Holder --

Family and other close relationships / Barbara S. McCrady -- Social contexts and substance use / Rudolf H. Moos -- Ethnography and applied substance misuse research : anthropological and cross-cultural factors / Robert G. Carlson -- Behavioral therapies : the glass would be half full if only we had a glass / Kathleen M. Carroll and Bruce J. Rounsaville -- Pharmacotherapy of addictive disorders / Stephanie S. O'Malley and Thomas R. Kosten -- Religion, spirituality and the troublesome use of substances / Keith Humphreys and Elizabeth Gifford -- What we need is a system : creating a responsive and effective substance abuse treatment system / A. Thomas McLellan -- Drawing the science together : ten principles, ten recommendations / William R. Miller and Kathleen M. Carroll